Stock Quotes in this Article: ACAD, ACUR, CLDX, EMKR, HOLI, ECYT, GALE, ZLCS

WINDERMERE, Fla. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst like a recent earnings release. Sometimes stocks making big-percentage moves have been hit with an analyst upgrade or an analyst upgrade.

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Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

With that in mind, let's take a closer look at a number of stocks under $10 that are making large-percentage moves to the upside today.

Acadia Pharmaceuticals

Acadia Pharmaceuticals (ACAD) is a biopharmaceutical company focused on the development and commercialization of small molecule drugs for the treatment of central nervous system disorders. This stock is trading up 16.6% at $2.18 in recent trading.

Today’s Range: $1.86-$2.21

52-Week Range: $0.90-$3.30

Volume: 1.8 million

Three-Month Average Volume: 416,028

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From a technical perspective, ACAD is spiking big today on monster volume. This sharp move higher has now pushed ACAD into breakout territory since the stock has moved above some near-term overhead resistance at $2.06.

Market players should continue to look for long-biased trades as long as ACAD is trending above $2.06 and it closes near its daily highs of $2.20. If we get that strong close today, then look for ACAD to hit $2.40 to $2.60 in the near future.

Endocyte

Endocyte (ECYT) is a biopharmaceutical company. Endocyte is engaged in developing therapies for the treatment of cancer and inflammatory diseases. This stock is trading up 12.2% at $5.50 in recent trading.

Today’s Range: $4.93-$5.78

52-Week Range: $3.02-$14.80

Volume: 2.2 million

Three-Month Average Volume: 867,048

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From a technical perspective, ECYT is ripping higher today off some near-term previous support at $4.83 with monster volume. This move is quickly pushing ECYT within range of triggering a big breakout. That breakout will trigger once ECYT takes out some near-term overhead resistance at $6.48 with volume.

Traders should now look for long-biased trades if EYCT can sustain a high-volume move and close over $6.48. Look for volume on that move that’s near or well above 867,048 shares. If we get that action soon, then look for ECYT to make a run at its 200-day moving average of $8.68 in the near future.

Hollysys Automation Technologies

Hollysys Automation Technologies (HOLI) is a provider of automation and control technologies and applications in the People’s Republic of China. This stock is trading up 7.8% at $10.10 in recent trading.

Today’s Range: $9.61-$10.30

52-Week Range: $4.54-$14.41

Volume: 221,000

Three-Month Average Volume: 274,149

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From a technical perspective, HOLI has started to bounce off its 50-day moving average today at $9.65 with decent volume. At last check, the stock hit a high today of $10.30, which sits right around some near-term overhead resistance at $10.35. Since hitting that high, the stock has pulled back to its current price of around $9.80.

Traders should now look for long biased trades only if HOLI takes out that near-term resistance at $10.35 with volume. Look for a sustained high-volume move and close over that level to signal that HOLI wants to trend higher.

Look for volume on that move that’s near or well above 274,149 shares. If we get that action soon, look for HOLI to re-test its recent high of $11.35.

Galena Biopharma

Galena Biopharma (GALE) is a biotechnology company focused on discovering, developing and commercializing therapies addressing unmet medical needs using RNAi-targeted and immunotherapy technologies. This stock is trading up 24.5% at $1.93 in recent trading.

Today’s Range: $1.66-$1.99

52-Week Range: $0.36-$1.71

Volume: 6.9 million

Three-Month Average Volume: 1.1 million

Shares of GALE are soaring higher today after the company received a notice of allowance patent for NeuVax in IHC1+/2+.

From a technical perspective, GALE is soaring higher today on monster volume. This huge move the upside today has now pushed the stock into breakout territory. That breakout triggered once GALE took out some near-term overhead resistance at $1.66 to $1.71 with volume.

Traders should continue to look for long biased trades in GALE as long as this stock closes above those breakout levels today and near its daily high. At last check, the daily high is $1.96. If we get a strong close today, look for GALE to continue its uptrend towards $2.50 or higher in the near future.

I also featured Galena in "5 Stocks Setting Up to Break Out."

Emcore

Emcore (EMKR) offers a portfolio of compound semiconductor-based products for the broadband, fiber optics, space and solar power markets. This stock is trading up 5.8% to $4.81 in recent trading.

Today’s Range: $4.51-$4.83

52-Week Range: $3.28-$12.40

Volume: 249,000

Three-Month Average Volume: 222,436

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From a technical perspective, EMKR is ripping higher today and moving back above its 50-day moving average of $4.75 on decent volume. As long as EMRK can manage to close above its 50-day, then traders should continue to look for long-biased trades.

This stock could have some juice back towards its 200-day moving average of $5.92, but again, make sure it continues to trend above its 200-day. It’s also worth noting that the upside volume for the last week has been tracking in very strong, so this stock could be under heavy accumulation.

Zalicus

Zalicus (ZLCS) is a biopharmaceutical company developing drug candidates with a focus on the treatment of pain and inflammation. This stock is trading up 2.9% to $1.07 in recent trading.

Today’s Range: $1.08-$1.16

52-Week Range: $0.82-$3.21

Volume: 3.5 million

Three-Month Average Volume: 941,213

From a technical perspective, ZLCS is gapping up strong today back above its 50-day moving average of $1.09 on monster volume.

Traders should continue to look for long biased trades as long as ZLCS is trending above its 50-day. The next major breakout trade will trigger for ZLCS once the stock takes out some near-term overhead resistance at $1.16 with volume. A sustained high-volume move and close above that level should set this stock up for some decent upside. Some potential upside targets are $1.36 to $1.54.

Celldex Therapeutics

Celldex Therapeutics (CLDX) is a biopharmaceutical company, which applies its Precision Targeted Immunotherapy Platform to generate a pipeline of candidates to treat cancer and other difficult-to-treat diseases. This stock is trading up 4.1% to $4.79 in recent trading.

Today’s Range: $4.65-$4.89

52-Week Range: $2.05-$5.66

Volume: 866,000

Three-Month Average Volume: 825,854

From a technical perspective, CLDX is moving sharply higher today on decent volume. This move has now pushed CLDX within range of triggering a near-term breakout. That breakout will hit once some overhead resistance at $5.19 is taken out with volume. Traders should look for long biased trades if $5.19 is taken out with volume that’s near or well above 825,854 shares. If we get that action soon, then look for CLDX to re-test its next significant overhead resistance level at $5.66 in the near future.

Celldex shows up on a recent list of 7 Cancer Drug Stocks to Know Right Now.

Acura Pharmaceuticals

Acura Pharmaceuticals (ACUR) is a specialty pharmaceutical company engaged in research, development and manufacture of product candidates providing abuse deterrent features and benefits utilizing its Aversion and Impede Technologies. This stock is trading up 6.7% to $4.14 in recent trading.

Today’s Range: $3.92-$4.20

52-week Range: $2.28-$6.80

Volume: 311,000

Three-Month Average Volume: 73,277

From a technical perspective, ACUR is ripping higher today on strong volume. This spike up has now pushed ACUR within range of triggering a big breakout trade. That breakout will hit once ACUR takes out $4.22 to $4.24 with high-volume.

Traders should look for a sustained high-volume move and close above those levels to signal that ACUR wants to trend much higher. If we get that action soon, then look for ACUR to hit re-test its next significant overhead resistance levels at $4.75 to $5.25 in the near future.

To see more stocks under-$10 that are making notable moves higher today, check out the Stocks Under-$10 Moving Higher portfolio on Stockpickr.

-- Written by Roberto Pedone in Winderemere, Fla.

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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Windermere, Fla., is an independent trader who focuses on stocks, options, futures, commodities and currencies. He is also an outside contributor to Beconequity.com and maintains the website Maddmoney.net, which he sold to Blue Wave Advisors in 2008. Roberto studied International Business at The Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany.