Stock Quotes in this Article: EBAY, ITRI, OSIR, YNDX, GRPN

WINDERMERE, Fla. (Stockpickr) -- Professional traders running mutual funds and hedge funds don’t just look at a stock’s price moves; they also track big changes in volume activity. Many times when above average volume moves into equity it precedes a large spike in volatility.

Major moves in volume can signal unusual activity, such as insider buying or selling -- or buying or selling by “superinvestors.”

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Unusual volume can also be a major signal that hedge funds and momentum traders are piling into a stock ahead of a catalyst. These types of traders like to get in well before a large spike, so it’s always a smart move to monitor unusual volume. That said, remember to combine trend and price action with unusual volume. Put them all together to help you decipher the next big trend for any stock.

With that in mind, let's take a look at several stocks rising on unusual volume today.

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Osiris Therapeutics

Osiris Therapeutics (OSIR) is a stem cell therapeutic company. It focuses on developing and marketing products to treat serious medical conditions in the inflammatory, autoimmune, orthopedic and cardiovascular areas. This stock is trading up 15.4% at $10.60 in recent trading.

Today’s Volume: 1.2 million

Average Volume: 205,531

Volume % Change: 861%

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From a technical perspective, OSIR is soaring here on monster volume. This move has triggered a near-term breakout trade once OSIR took out Friday’s high of $9.40 with heavy volume. That said, OSIR has now entered extremely overbought territory since its current relative strength index reading is 81.27.

Traders should now only look for long-biased trades if OSIR is trending above today’s high with strong upside volume flows. At last check, this stock has hit an intraday high of $11.58. I would consider any upside volume action that’s near or above 205,531 shares as bullish. If OSIR fails to take out today’s high with volume, then traders should wait for a significantly pullback off overbought levels before getting interested in this stock.

Itron

Itron (ITRI) is a technology company that delivers end-to-end smart metering solutions to electric, natural gas, and water utilities worldwide. This stock is trading up 5% at $39.41 in recent trading.

Today’s Volume: 552,000

Average Volume: 435,915

Volume % Change: 124%

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From a technical perspective, ITRI is ripping higher here back above both its 50-day and 200-day moving averages with above-average volume. This move is quickly pushing the stock within range of triggering a near-term breakout trade. That trade will hit once ITRI takes out some near-term overhead resistance at $41 with volume.

Traders should now look for long-biased trades as long as ITRI is trending above its 50-day at $39.13, and once it sustains a move or close above $41 with volume that’s near or above 435,915 shares. If we get that action soon, then look for ITRI to possibly hit its next significant overhead resistance level at $45.12 in the near future.

Yandex

Yandex (YNDX) operates an Internet search engine in Russia and internationally. This stock is trading up 5.5% at $18.54 in recent trading.

Today’s Volume: 1.8 million

Average Volume: 1.6 million

Volume % Change: 122%

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From a technical perspective, YNDX is ripping higher here on above average volume. This move is coming off a near-term low of $16.65 that also coincided with an oversold condition. This stock recently became oversold once its RSI reading hit below 30.

Traders should now look for long-biased trades if YNDX can manage to trigger a near-term breakout trade. That trade will hit once YNDX takes out some near-term overhead resistance at $19.32 to $19.48 with high volume. Look for a sustained move or close above those levels with volume that’s near or above 1.6 million shares. If we get that action soon, then YNDX could hit $21 to its 50-day moving average of $22.18 in the near future.

Groupon

Groupon (GRPN) is a local e-commerce marketplace that connects merchants to consumers by offering goods and services at a discount. This stock is trading up 12.4% at $11.32 in recent trading.

Today’s Volume: 8 million

Average Volume: 5.1 million

Volume % Change: 154%
Shares of GRPN are ripping higher today after Morgan Stanley raised its rating on the stock to overweight from equalweight, with an $18 price target, citing the company’s revenue growth acceleration in North America and due to diminished concerns about its competition.

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From a technical perspective, GRPN is skyrocketing higher here on above average volume. This move is quickly pushing GRPN within range of triggering a near-term breakout trade. That trade will hit once GRPN takes out its 50-day moving average of $11.35 with highmoving average volume. At last check, GRPN has hit an intraday high of $11.35.

Traders should now look for long-biased trades if GRPN can sustain a move or close above $11.35 with volume that’s near or above 5,053,210 shares. If we get that action soon, then GRPN should re-test its next significant overhead resistance levels at $12.43 to just above $13.

Groupon shows up on a recent list of 2 Recent IPOs to Sell.

Icon

Icon (ICLR) is a contract research organization, providing outsourced development services on a global basis to the pharmaceutical, biotechnology and medical device industries. This stock is trading up 2% at $21.87 in recent trading.

Today’s Volume: 322,000

Average Volume: 201,964

Volume % Change: 174%

Shares of ICLR are moving modestly higher today after William Blair upgraded the stock to outperform from market perform.

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From a technical perspective, ICLR is moving modestly higher here as the stock pushes back above its 50-day moving average of $21.75 with above average volume. This move is quickly pushing the stock within range of a near-term breakout trade. That trade will hit once ICLR takes out some near-term overhead resistance at $23 with high volume.

Traders should now look for long-biased trades if ICLR can sustain a move or close above those levels with volume that’s near or above 201,964 shares. If we get that action soon, then look for ICLR to re-test and possibly take out its April high of $23.81.

Icon was one of 10 Top Morningstar M&A Stock Picks for 2012.

eBay

eBay (EBAY) is a global commerce platform. This stock is trading up 4.5% at $42.53 in recent trading.

Today’s Volume: 14.2 million

Average Volume: 12.8 million

Volume % Change: 66%.

Shares of EBAY are ripping higher today after KBW initiated coverage on the stock with an outperform rating and a $50 price target, citing the company’s leadership position in e-commerce and industry growth should boost earnings and sales.

From a technical perspective, EBAY is moving sharply higher here on above average volume, and the stock has started to enter major breakout territory. That move has started now that EBAY has taken out some near-term overhead resistance at $41.72 to $41.96 with high-volume.

Traders should continue to look for long-biased trades as long as EBAY is trending above those levels with strong upside volume flows. I would consider any upside volume day that registers near or above 12.8 million shares as bullish. If we continue to see that action, then EBAY should easily hit $45 or higher in the near future.

eBay shows up on a recent list of 10 New Stocks on All-Star Fund Mangers' List.

BroadVision

BroadVision (BVSN) is a provider of electronic commerce business solutions. It delivers a combination of technologies and services into the global market. This stock is trading up 9% at $13.60 in recent trading.

Today’s Volume: 553,000

Average Volume: 330,464

Volume % Change: 261%.

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From a technical perspective, BVSN is ripping higher here with above average volume. This move is coming off extremely oversold conditions that were created once BVSN plunged from its March high of $56.46 to a recent low of $9.51. That massive selloff pushed this stock into oversold territory with its RSI reading coming in at below 30 since mid-May.

Traders should now look for long-biased trades once BVSN triggers a near-term breakout trade. That trade will hit once BVSN takes out some near-term overhead resistance at $14.99 with high volume. Look for a sustained move or close above $14.99 with volume that’s near or above 330,464 shares. If we get that action soon, then look for BVSN to tag its 50-day moving average of $18.29 in the near future.

ACI Worldwide

ACI Worldwide (ACIW) develops, markets, installs and supports a line of software products and services primarily focused on facilitating electronic payments. This stock is trading up 3.3% at $41.90 in recent trading.

Today’s Volume: 330,000

Average Volume: 308,383

Volume % Change: 80%.

From a technical perspective, ACIW is moving notably higher here on above average volume, and this stock has briefly entered breakout territory. That move into breakout territory started when ACIW took one some past overhead resistance at $41.99. At last check, ACIW has hit an intraday high of $43 but has since pulled back to its current price near $42.

Traders should now look for long-biased trades as long as ACIW is trending above $41.99 to $43 with strong upside volume flows. I would consider any upside volume day that registers near or above 308,383 shares as bullish. If we get that action, look for ACIW to hit $45 to $50 in the near future.

To see more stocks rising on unusual volume, check out the Stocks Rising On Unusual Volume portfolio on Stockpickr.

-- Written by Roberto Pedone in Winderemere, Fla.

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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Windermere, Fla., is an independent trader who focuses on stocks, options, futures, commodities and currencies. He is also an outside contributor to Beconequity.com and maintains the website Maddmoney.net, which he sold to Blue Wave Advisors in 2008. Roberto studied International Business at The Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany.