Stock Quotes in this Article: DRRX, ECTE, GTXI, PTIX, XNPT, ZHNE

DELAFIELD, Wis. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside today.

Echo Therapeutics (ECTE)

This company is a transdermal medical device company with skin permeation technology. This stock closed up 5.4% to $2.88 in Tuesday's trading session.

Tuesday's Range: $2.75-$2.99

52-Week Range: $1.80-$18.90

Tuesday's Volume: 140,000

Three-Month Average Volume: 217,495

From a technical perspective, ECTE bounced sharply higher here right above its 50-day moving average at $2.64 with decent upside volume. This move is quickly pushing shares of ECTE within range of triggering a big breakout trade. That trade will hit if ECTE manages to clear Tuesday's intraday high of $2.99 and then once it takes out more resistance at $3.30 with high volume.

Traders should now look for long-biased trades in ECTE as long as it's trending above its 50-day at $2.64 or above more near-term support at $2.50, and then once it sustains a move or close above those breakout levels with volume that hits near or above 217,495 shares. If that breakout triggers soon, then ECTE will set up to re-test or possibly take out its next major overhead resistance levels at $4 to $4.50.

Durect (DRRX)

This is a specialty pharmaceutical company. It develops pharmaceutical products based on its proprietary drug delivery technology platforms. This stock closed up 7.1% to $1.20 in Tuesday's trading session.

Tuesday's Range: $1.12-$1.23

52-Week Range: $0.61-$1.85

Tuesday's Volume: 959,000

Three-Month Average Volume: 660,808

From a technical perspective, DRRX spiked sharply higher here right off its 200-day moving average of $1.11 and back above its 50-day moving average of $1.15 with strong upside volume. This move also pushed shares of DRRX into breakout territory, since the stock took out some near-term overhead resistance at $1.19. Shares of DRRX are now starting to trend within range of triggering a big breakout trade above some stiff overhead resistance. That trade will hit if DRRX manages to take out Tuesday's intraday high of $1.23 and then once it clears some key overhead resistance at $1.34 with high volume.

Traders should now look for long-biased trades in DRRX as long as it's trending above its 200-day at $1.11 or above more near-term support at $1.07, and then once it sustains a move or close above those breakout levels with volume that hits near or above 660,808 shares. If that breakout triggers soon, then DRRX will set up to re-fill some of its previous gap down zone from May that started near $1.70.

Zhone Technologies (ZHNE)

This company designs, develops and manufactures communications network equipment for telecommunications, wireless and cable operators worldwide. This stock closed up 7.1% to $3.14 in Tuesday's trading session.

Tuesday's Range: $2.88-$3.37

52-Week Range: $0.40-$3.48

Tuesday's Volume: 2.44 million

Three-Month Average Volume: 781,497

From a technical perspective, ZHNE bounced sharply higher here right above some near-term support at $2.44 with heavy upside volume. This stock has been uptrending strong for the last few weeks, with shares moving higher from its low of $2.20 to its intraday high of $3.37. During that move, shares of ZHNE have been consistently making higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of ZHNE within range of triggering a major breakout trade. That trade will hit if ZHNE manages to take out Tuesday's intraday high of $3.37 and then once it clears its 52-week high at $3.48 with high volume.

Traders should now look for long-biased trades in ZHNE as long as it's trending above some key near-term support at $2.44, and then once it sustains a move or close above those breakout levels with volume that hits near or above 781,497 shares. If that breakout hits soon, then ZHNE will set up to enter new 52-week high territory, which is bullish technical price action. Some possible upside targets off that breakout are $4 to $4.50.

XenoPort (XNPT)

This is a biopharmaceutical company focused on developing and commercializing a portfolio of internally discovered product candidates with an initial focus on neurological disorders. This stock closed up 17.1% to $5.89 in Tuesday's trading session.

Tuesday's Range: $5.10-$6.08

52-Week Range: $4.24-$12.98

Tuesday's Volume: 1.63 million

Three-Month Average Volume: 365,431

From a technical perspective, XNPT skyrocketed higher here right off its 50-day moving average of $5.09 with heavy upside volume. This stock has been uptrending strong for the last few weeks, with shares moving higher from its low of $4.24 to its intraday high of $6.08. During that uptrend, shares of XNPT have been consistently making higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of XNPT within range of triggering a near-term breakout trade. That trade will hit if XNPT manages to take out Tuesday's intraday high of $6.08 with high volume.

Traders should now look for long-biased trades in XNPT as long as it's trending above $5.70 to $5.26, and then once it sustains a move or close above $6.08 with volume that hits near or above 365,431 shares. If that breakout triggers soon, then XNPT will set up to re-fill some of its previous gap down zone from May that started at $6.83. Any high-volume move above $6.83 will then give XNPT a chance to tag $7 to $7.50.

Performance Technologies (PTIX)

This company is a supplier of advanced network communications solutions to carrier, government and OEM markets. This stock closed up 19.9% to $3.43 in Tuesday's trading session.

Tuesday's Range: $2.86-$3.44

52-Week Range: $0.73-$3.97

Tuesday's Volume: 920,000

Three-Month Average Volume: 194,859

From a technical perspective, PTIX skyrocketed higher here and broke out above some near-term overhead resistance levels at $3.20 to $3.43 with high volume. This stock has been trending sideways for the last month, with shares moving between $2.59 on the downside and $3.43 on the upside. This move has started to push shares of PTIX within range of triggering a big breakout trade. That trade will hit if PTIX manages to take out Tuesday's intraday high of $3.44 and then once it clears its 52-week high at $3.97 with high volume.

Traders should now look for long-biased trades in PTIX as long as it's trending above $3.20 or $3, and then once it sustains a move or close above those breakout levels with volume that's near or above 194,859 shares. If that breakout hits soon, then PTIX will set up to enter new 52-week high territory, which is bullish technical price action. Some possible upside targets off that breakout are $5 to $6.

GTX (GTXI)

This is a biopharmaceutical company dedicated to the discovery, development and commercialization of small molecules that selectively target hormone pathways to treat cancer, osteoporosis and bone loss, muscle loss and other serious medical condition. This stock closed up 5.3% to $1.59 in Tuesday's trading session.

Tuesday's Range: $1.53-$1.63

52-Week Range: $1.31-$7.24

Tuesday's Volume: 1.50 million

Three-Month Average Volume: 1.25 million

From a technical perspective, GTXI ripped sharply higher here right off some near-term support at $1.50 with strong upside volume. This move is quickly pushing shares of GTXI within range of triggering a major breakout trade. That trade will hit if GTXI manages to take out some near-term overhead resistance at Tuesday's intraday high of $1.63 to more resistance at $1.67 with high volume.

Traders should now look for long-biased trades in GTXI as long as it's trending above support at $1.50 or above its recent low of $1.31, and then once it sustains a move or close above those breakout levels with volume that hits near or above 1.25 million shares. If that breakout hits soon, then GTXI will set up to re-fill some of its previous gap down zone from August that started just above $4. Some possible upside targets for GTXI if it gets into that gap with volume are $2 to $2.50.

-- Written by Roberto Pedone in Delafield, Wis.

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>>5 Tech Stocks Spiking on Big Volume

>>5 Stocks Setting Up to Break Out

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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.