Stock Quotes in this Article: CBMX, GTXI, RIGL, MEIP, ANAC

MADISON, Wis. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

>>5 Stocks Under $10 Set to Soar

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside today.

>>5 Stocks Fund Managers Love for 2013

MEI Pharma

MEI Pharma (MEIP) is developing cancer therapeutics based on the central design of naturally occurring compounds called isoflavones. This stock closed up 3.8% to $8.88 onThursday.

Thursday's Range: $8.30-$9.19

52-Week Range: $1.98-$13.20

Volume: 325,000

Three-Month Average Volume: 86,000

From a technical perspective, MEIP ripped higher here right above its 50-day moving average of $7.63 with heavy upside volume. This move is quickly pushing shares of MEIP within range of triggering a major breakout trade. That trade will hit if MEIP manages to take out some near-term overhead resistance levels at $9.01 to $9.40 and then once it clears more resistance at $9.65 to $10.08 with high volume. At last check, MEIP hit an intraday high of $9.19 and volume was well above its three-month average action of 86,000 shares.

Traders should now look for long-biased trades in MEIP as long as it’s trending above Thursday’s low of $8.30 or above its 50-day at $7.63, and then once it sustains a move or close above those breakout levels with volume that hits near or above 86,000 shares. If that breakout triggers soon, then MEIP will set up to re-test or possibly take out its next major overhead resistance levels at $12 to $13.18.

Anacor Pharmaceuticals

Anacor Pharmaceuticals (ANAC) is engaged in the discovery, development and commercialization of novel small molecule therapeutics derived from its novel boron chemistry platform. This stock closed up 9.9% to $7.06 on Thursday.

Thursday's Range: $6.40-$7.13

52-Week Range: $3.00-$7.34

Volume: 510,000

Three-Month Average Volume: 675,000

From a technical perspective, ANAC soared higher here right off some near-term support at $6.30 with lighter-than-average volume. This stock recently gapped up sharply from around $4 to $7 with heavy upside volume. Shares of ANAC continue to uptrend after that gap up move, and it’s now quickly moving within range of triggering a major breakout trade. That trade will hit if ANAC manages to take out some key overhead resistance levels at $7.34 to $7.55 with high volume.

Traders should now look for long-biased trades in ANAC as long as it’s trending above some key near-term support at $6.30 and then once it sustains a move or close above those breakout levels with volume that hits near or above 675,000 shares. If that breakout triggers soon, then ANAC will set up to re-test or possibly take out its next major overhead resistance levels at $8.30 to $9.

CombiMatrix

CombiMatrix (CBMX) is a molecular diagnostics company that operates mainly in the field of genetic analysis and molecular diagnostics. This stock closed up 10.1% to $3.36 on Thursday.

Thursday's Range: $3.04-$3.45

52-Week Range: $1.40-$14.14

Volume: 477,000

Three-Month Average Volume: 765,000

From a technical perspective, CBMX bounced sharply higher here right off some near-term support at $2.95 with lighter-than-average volume. This bounce is coming right above some key near-term support levels at $2.80 to $2.97. Shares of CBMX are now quickly moving within range of triggering a near-term breakout trade. That trade will hit if CBMX manages to clear its 50-day moving average at $3.52 and then once it takes out more resistance at $3.59 with high volume.

Traders should now look for long-biased trades in CBMX as long as it’s trending above Thursday’s low of $3.05 and then once it sustains a move or close above those breakout levels with volume that hits near or above 765,000 shares. If that breakout triggers soon, then CBMX will set up re-test or possibly take out its next major overhead resistance levels at $4.62 to $5.

GTX

GTX (GTXI) is biopharmaceutical company dedicated to the discovery, development and commercialization of small molecules that selectively target hormone pathways to treat cancer, osteoporosis and bone loss, muscle loss and other serious medical condition. This stock closed up 6.6% to $4.36 on Thursday.

Thursday's Range: $4.12-$4.45

52-Week Range: $2.62-$5.41

Volume: 512,000

Three-Month Average Volume: 121,000

From a technical perspective, GTXI bounced higher here right above some near-term support at $4 to $3.90 and back above its 200-day moving average at $4.23 with heavy upside volume. This bounce is occurring after shares of GTXI had been downtrending for the last three months, with shares falling from $5.41 to its recent low of $3.85. Shares of GTXI are now quickly moving within range of triggering a near-term breakout trade. That trade will hit if GTXI manages to take out its 50-day at $4.47 and then once it clears more resistance at $4.57 to $4.64 with high volume.

Traders should now look for long-biased trades in GTXI as long as it’s trending above its 200-day at $4.23 or above $3.90 and then once it sustains a move or close above those breakout levels with volume that hits near or above 121,000 shares. If that breakout triggers soon, then GTXI will set up to re-test or possibly take out its next major overhead resistance levels at $4.90 to $5.16. Any high-volume move above $5.16 will then put $5.40 into focus for shares of GTXI.

Rigel Pharmaceuticals

Rigel Pharmaceuticals (RIGL) is a clinical-stage drug development company that discovers and develops novel, small-molecule drugs for the treatment of inflammatory/autoimmune diseases, as well as for certain cancers and metabolic diseases. This stock closed up 1.4% to $4.70 on Thursday.

Thursday's Range: $4.53-$4.73

52-Week Range: $4.41-$11.44

Volume: 1.28 million

Three-Month Average Volume: 765,000

From a technical perspective, RIGL spiked modestly higher here right above some near-term support levels at $4.43 to $4.41 with heavy upside volume. This stock recently gapped down sharply from over $7.50 to its recent low of $4.41 with heavy downside volume. Following that gap down, shares of RIGL have started o stabilize and consolidate above its recent lows. That action is now starting to push shares of RIGL within range of triggering a major breakout trade. That trade will hit if RIGL manages to take out some near-term overhead resistance at $4.81 and then once it takes out its gap down day high of $5.14 with high volume.

Traders should now look for long-biased trades in RIGL as long as it’s trending above $4.43 to $4.41 and then once it sustains a move or close above those breakout levels with volume that hits near or above 765,000 shares. If that breakout triggers soon, then RIGL will set up to re-fill some of its previous gap down zone that started above $7.50. Some possible upside targets are $6 to its 50-day moving average at $6.42.

To see more stocks that are making notable moves higher today, check out the Stocks Under $10 Moving Higher portfolio on Stockpickr.

-- Written by Roberto Pedone in Winderemere, Fla.

RELATED LINKS:

>>4 Big Stocks on Traders' Radars
>>5 Consumer Stocks Ready to Push Higher

>>4 Turnaround Stocks With Major Upside

Follow Stockpickr on Twitter and become a fan on Facebook.

At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Madison, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.