Stock Quotes in this Article: ECTE, RGDX, SMA, TSPT

DELAFIELD, Wis. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

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Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

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With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside today.

Echo Therapeutics

Echo Therapeutics (ECTE) is a transdermal medical device company with skin permeation technology. This stock closed up 14.6% to $3.06 a share in Thursday's trading session.

Thursday's Range: $2.71-$3.60

52-Week Range: $1.80-$16.00

Thursday's Volume: 959,000

Three-Month Average Volume: 163,722

From a technical perspective, ECTE exploded higher here right off its 50-day moving average of $2.70 with heavy upside volume. This move briefly pushed shares of ECTE into breakout territory, since the stock flirted with some near-term overhead resistance levels at $3.10 to $3.40. Shares of ECTE pulled back dramatically off its intraday high of $3.60 to close at $3.06. Despite that pullback, shares of ECTE still have a bullish look if the stock can remain above its 50-day and take out Thursday's high soon.

Traders should now look for long-biased trades in ECTE as long as it's trending above its 50-day at $2.70 and then once it sustains a move or close above Thursday's high of $3.60 with volume that hits near or above 163,722 shares. If we get that move soon, then ECTE will set up to re-test or possibly take out its next major overhead resistance levels at $4 to $5, or even its 200-day moving average at $5.60.

Symmetry Medical

Symmetry Medical (SMA) designs, develops and produces medical device solutions and surgical instruments. This stock closed up 2.6% to $8.28 in Thursday's trading session.

Thursday's Range: $8.07-$8.28

52-Week Range: $7.44-$12.83

Thursday's Volume: 85,000

Three-Month Average Volume: 137,065

From a technical perspective, SMA trended modestly higher here with lighter-than-average volume. This stock has been trending sideways and consolidating for the last month and change, with shares moving between $7.76 on the downside and $8.54 on the upside. Shares of SMA are starting to trend within range of its 50-day moving average at $8.33 and within range of triggering a breakout trade. That trade will hit if SMA manages to take out the upper-end of its recent range at $8.48 to $8.54 with high volume.

Traders should now look for long-biased trades in SMA as long as it's trending above some key near-term support levels at $7.90 or at $7.76 and then once it sustains a move or close above those breakout levels with volume that hits near or above 137,065 shares. If that breakout hits soon, then SMA will set up to re-test or possibly take out its next major overhead resistance levels at $9.41 to its 200-day at $9.77. Any high-volume move above $9.77 will then put $10.50 into range for shares of SMA.

Transcept Pharmaceuticals

Transcept Pharmaceuticals (TSPT) is a specialty pharmaceutical company focused on the development and commercialization of proprietary products that address important therapeutic needs in neuroscience. This stock closed up 2.6% to $8.28 in Thursday's trading session.

Thursday's Range: $3.60-$3.67

52-Week Range: $2.52-$6.77

Thursday's Volume: 92,000

Three-Month Average Volume: 165,940

From a technical perspective, TSPT trended modestly higher here with lighter-than-average volume. This stock recently made a sharp run higher right off its 50-day moving average of $3.03 to its recent high of $3.70 with decent upside volume flows. That move has now pushed shares of TSPT within range of triggering a big breakout trade. That trade will hit if TSPT manages to take out some near-term overhead resistance levels at $3.70 to $3.90 and then once it clears its 200-day at $4.02 and more past resistance at $4.23 with high volume.

Traders should now look for long-biased trades in TSPT as long as it's trending above support just below $3.40 and then once it sustains a move or close above those breakout levels with volume that hits near or above 165,940 shares. If that breakout hits soon, then TSPT will set up to re-test or possibly take out its next major overhead resistance levels at $5 to $5.50.

Response Genetics

Response Genetics (RGDX) is a life sciences company, engaged in the research and development of innovative clinical diagnostic tests for cancer based on its proprietary technologies. This stock closed up 7.1% to $2.24 in Thursday's trading session.

Thursday's Range: $2.10-$2.31

52-Week Range: $0.99-$2.93

Thursday's Volume: 171,000

Three-Month Average Volume: 112,448

From a technical perspective, RGDX ripped sharply higher here back above its 50-day moving average of $2.16 with above-average volume. This stock has been uptrending strong for the last five months, with shares soaring higher from its low of $1.32 to its recent high of $2.93. During that uptrend, shares of RGDX have been making mostly higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of RGDX within range of triggering a near-term breakout trade. That trade will hit if RGDX manage to take out Thursday's high of $2.32 and then once it clears more resistance levels at $2.45 to $2.60 with high volume.

Traders should now look for long-biased trades in RGDX as long as it's trending above some key near-term support levels at $2 or at $1.91 and then once it sustains a move or close above those breakout levels with volume that hits near or above 112,448 shares. If that breakout hits soon, then RGDX will set up to re-test or possibly take out its 52-week high at $2.93. Any high-volume move above $2.93 to $3.05 will then give RGDX a chance to tag $3.50 to $4.

To see more stocks that are making notable moves higher today, check out the Stocks Under $10 Moving Higher portfolio on Stockpickr.

-- Written by Roberto Pedone in Delafield, Wis.


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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including

CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.