Stock Quotes in this Article: PDII, TSPT, ZLC, TROV

MADISON, Wis. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

>>5 Stock Charts You Need to See

Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

>>5 Stocks With Big Insider Buying

With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside today.

TrovaGene

TrovaGene (TROV) is a development stage molecular diagnostic company that focuses on the development and marketing of urine-based nucleic acid tests for patient/disease screening and monitoring. This stock closed up 8.7% to $6.56 on Thursday.

Thursday's Range: $6.20-$6.65

52-Week Range: $2.09-$8.96

Volume: 250,000

Three-Month Average Volume: 90,070

>>5 Stocks Spiking on Unusual Volume

From a technical perspective, TROV ripped higher here back above its 50-day moving average of $6.32 with above-average volume. This move is quickly pushing shares of TROV within range of triggering a major breakout trade. That trade will hit if TROV manages to take out some near-term overhead resistance levels at $6.80 to $7.23 and then once it clears some past resistance at $7.40 with high volume.

Traders should now look for long-biased trades in TROV as long as it's trending above its 50-day at $6.32 and then once it sustains a move or close above those breakout levels with volume that hits near or above 90,070 shares. If that breakout triggers soon, then TROV will set up to re-test or possibly take out its next major overhead resistance levels at $8.50 to its all-time high at $8.96. Any high-volume move above its all-time high will then give TROV a chance to trend north of $10.

Transcept Pharmaceuticals

Transcept Pharmaceuticals (TSPT) is a specialty pharmaceutical company focused on the development and commercialization of proprietary products that address important therapeutic needs in neuroscience. This stock closed up 7.4% to $3.02 on Thursday.

Thursday's Range: $2.81-$3.03

52-Week Range: $2.81-$6.81

Volume: 140,000

Three-Month Average Volume: 149,211

>>5 Stocks Under $10 Set to Soar

From a technical perspective, TSPT bounced sharply higher here right around some previous support levels at $2.90 to $2.87 with decent upside volume. This stock has been downtrending badly for the last five months, with shares plunging from its high of $6.77 to its intraday low of $2.81. During that move, shares of TSPT have been consistently making lower highs and lower lows, which is bearish technical price action. That said, shares of TPST could be marking a bottom here near $2.90 to $2.80, since the stock has held those levels for the last month and change.

Traders should now look for long-biased trades in TSPT as long as it's trending above $2.80 and then once it sustains a move or close above some near-term overhead resistance levels at $3.10 to $3.25 and above $3.31 to $3.40 with volume that hits near or above 149,211 shares. If that breakout triggers soon, then TSPT will set up to re-test or possibly take out its next major overhead resistance levels at $4.25 to $5.

Zale

Zale (ZLC) is a specialty retailer of fine jewelry in North America. This stock closed up 5.5% to $9.15 on Thursday.

Thursday's Range: $8.71-$9.21

52-Week Range: $2.42-$9.85

Volume: 763,000

Three-Month Average Volume: 783,269

>>5 Stocks the Pros Love This Summer

From a technical perspective, ZLC spiked higher here right above some near-term support at $8 with decent upside volume. This stock has been uptrending strong for the last two months, with shares soaring higher from its low of $3.76 to its recent high of $9.85. During that uptrend, shares of ZLC have been consistently making higher lows and higher highs, which is bullish technical price action. That move has now pushed this stock within range of triggering a near-term breakout trade. That trade will hit if ZLC manages to take out some near-term overhead resistance levels at $9.50 to its 52-week high at $9.85 with high volume.

Traders should now look for long-biased trades in ZLC as long as it's trending above some near-term support levels at $8.50 or $8 and then once it sustains a move or close above those breakout levels with volume that hits near or above 783,269 shares. If that breakout triggers soon, then ZLC will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $12 to $14.

PDI

PDI (PDII) provides outsourced commercial services to established and emerging pharmaceutical, biotechnology and health care companies in the U.S. This stock closed up 7.2% to $4.45 on Thursday.

Thursday's Range: $4.16-$4.53

52-Week Range: $3.82-$8.57

Volume: 78,000

Three-Month Average Volume: 57,556

>>5 Toxic Stocks You Need to Sell

From a technical perspective, PDII trended higher here right above some near-term support at $4.08 and back above its 50-day moving average at $4.41 with above-average volume. This move is quickly pushing shares of PDII within range of triggering a major breakout trade, which will hit if PDII manages to take out some near-term overhead resistance levels at $4.60 to $4.77 and then once it clears more resistance around $5 with high volume.

Traders should now look for long-biased trades in PDII as long as it's trending above some near-term support at $4.08 and then once it sustains a move or close above those breakout levels with volume that hits near or above 57,556 shares. If that breakout triggers soon, then PDII will set up to re-test or possibly take out its next major overhead resistance levels at $5.99 to its 200-day at $6.37.

To see more stocks that are making notable moves higher today, check out the Stocks Under $10 Moving Higher portfolio on Stockpickr.

-- Written by Roberto Pedone in Madison, Wis.

RELATED LINKS:

>>3 Hot Stocks to Trade (or Not)
>>5 Short-Squeeze Stocks Primed to Pop

>>5 Earnings Stocks the Bears Hate -- but You Should Love

Follow Stockpickr on Twitter and become a fan on Facebook.

At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Madison, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.