Stock Quotes in this Article: CLNE, EZCH, FSYS, OSIR

WINDERMERE, Fla. (Stockpickr) -- Professional traders running mutual funds and hedge funds don’t just look at a stock’s price moves; they also track big changes in volume activity. Often when above-average volume moves into an equity, it precedes a large spike in volatility.

Major moves in volume can signal unusual activity, such as insider buying or selling -- or buying or selling by “superinvestors.”

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Unusual volume can also be a major signal that hedge funds and momentum traders are piling into a stock ahead of a catalyst. These types of traders like to get in well before a large spike, so it’s always a smart move to monitor unusual volume. That said, remember to combine trend and price action with unusual volume. Put them all together to help you decipher the next big trend for any stock.

With that in mind, let's take a look at several stocks rising on unusual volume today.

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Clean Energy Fuels

Clean Energy Fuels (CLNE) is engaged in the business of selling natural gas fueling solutions to its customers mainly in the U.S. and Canada. This stock is trading up 4.4% at $13.92 in recent trading.

Today’s Volume: 1.43 million

Average Volume: 1.16 million

Volume % Change: 98%

Shares of CLNE are ripping higher here after Ascendiant Capital initiated the stock with a buy rating and a $15.50 price target.

From a technical perspective, CLNE is trending higher here right off its 200-day moving average of $13.38 with above-average volume. This move has pushed shares of CLNE into breakout territory, since the stock has taken out some near-term overhead resistance at $13.62. Shares of CLNE are now quickly moving within range of triggering another major breakout trade. That trade will hit if CLNE manages to take out some key overhead resistance levels at $14.37 to $14.69 with high volume.

Traders should now look for long-biased trades in CLNE as long as it’s trending above its 200-day at $13.38 or above $13.62, and then once it sustains a move or close above those breakout levels with high volume that hits near or above 1.16 million shares. If that breakout triggers soon, then CLNE will set up to re-test or possibly take out its next major overhead resistance level at $16.75.

EZchip Semiconductor

EZchip Semiconductor (EZCH) is engaged in the development and marketing of solutions and Internet applications to improve the connectivity and performance of corporate LAN and WAN. This stock is trading up 1.5% to $24.16 in recent trading.

Today’s Volume: 1.42 million

Average Volume: 444,507

Volume % Change: 428%

From a technical perspective, EZCH is ripping higher here right off its 52-week low of $21.80 with monster upside volume. That 52-week low was hit on an intraday basis, and now shares of EZCH are quickly moving within range of triggering a major breakout trade. That trade will hit if EZCH manages to take out some near-term overhead resistance at $25.45 with high volume.

Traders should now look for long-biased trades in EZCH as long as it’s trending above $23.50, and then once it sustains a move or close above $25.45 with volume that hits near or above 444,507 shares. If that breakout hits soon, then EZCH will set up to re-test or possibly take out its next major overhead resistance level at $27.21. Any high-volume move above $27.21 will then put its 50-day moving average at $29.97 into range for shares of EZCH.

Osiris Therapeutics

Osiris Therapeutics (OSIR) is a stem cell therapeutic company focused on developing and marketing products to treat medical conditions in the inflammatory, orthopedic and cardiovascular areas. This stock is trading up 5.7% at $10.10 in recent trading.

Today’s Volume: 167,000

Average Volume: 90,345

Volume % Change: 157%

From a technical perspective, OSIR is soaring higher here right above its 200-day moving average of $9.08 with above-average volume. This move is quickly pushing shares of OSIR within range of triggering a near-term breakout trade. That trade will hit of OSIR manages to clear some near-term overhead resistance levels at $10.36 to $10.84 with high volume.

Traders should now look for long-biased trades in OSIR as long as it’s trending above today’s low of $9.55, and then once it sustains a move or close above those breakout levels with volume that hits near or above 90,345 shares. If that breakout triggers soon, then OSIR will set up to re-test or possibly take out its next major overhead resistance levels at $11.94 to $12.08. Any high-volume move above those levels will then put $13 to $14.46 into range for shares of OSIR.

Fuel Systems Solutions

Fuel Systems Solutions (FSYS) designs, manufactures and supplies alternative fuel components and systems for use in the transportation, industrial and power generation industries on a global basis. This stock is trading up 3.8% at $16.23 in recent trading.

Today’s Volume: 344,000

Average Volume: 160,451

Volume % Change: 279%

From a technical perspective, FSYS is soaring higher here back above its 200-day moving average of $15.91 with above-average volume. This stock recently broke out above some near-term overhead resistance levels at $15.09 to $15.80 with high volume.

Traders should now look for long-biased trades in FSYS as long as it’s trending above its 200-day at $15.91 with strong upside volume flows. I would consider any upside volume day that registers near or above 160,451 shares as bullish. If FSYS can maintain that trend, then this stock will set up to re-test or possibly take out its next major overhead resistance levels at $17.50 to $19.

To see more stocks rising on unusual volume, check out the Stocks Rising On Unusual Volume portfolio on Stockpickr.

-- Written by Roberto Pedone in Winderemere, Fla.

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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Windermere, Fla., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.