Stock Quotes in this Article: DWA, NSM, OSIR, NRGM

DELAFIELD, Wis. (Stockpickr) -- Professional traders running mutual funds and hedge funds don't just look at a stock's price moves; they also track big changes in volume activity. Often when above-average volume moves into an equity, it precedes a large spike in volatility.

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Major moves in volume can signal unusual activity, such as insider buying or selling -- or buying or selling by "superinvestors."

Unusual volume can also be a major signal that hedge funds and momentum traders are piling into a stock ahead of a catalyst. These types of traders like to get in well before a large spike, so it's always a smart move to monitor unusual volume. That said, remember to combine trend and price action with unusual volume. Put them all together to help you decipher the next big trend for any stock.

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With that in mind, let's take a look at several stocks rising on unusual volume today.

Osiris Therapeutics

Osiris Therapeutics (OSIR) is a stem cell therapeutic company focused on developing and marketing products to treat medical conditions in the inflammatory, orthopedic and cardiovascular areas. This stock closed up 5.5% at $11.20 on Friday.

Friday's Volume: 246,000

Average Volume: 89,792

Volume % Change: 206%

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From a technical perspective, OSIR ripped higher here right off its 50-day moving average of $10.57 with above-average volume. This move also pushed shares of OSIR into breakout territory, since the stock took out some near-term overhead resistance at $10.90. Shares of OSIR are now quickly moving within range of triggering another key breakout trade. That trade will hit if OSIR manages to take out some near-term overhead resistance levels at $11.66 to its 52-week high at $11.94 with high volume.

Traders should now look for long-biased trades in OSIR as long as it's trending above Friday's low of $10.30 and then once it sustains a move or close above those breakout levels with volume that hits near or above 89,792 shares. If that breakout triggers soon, then OSIR will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that breakout are its next major overhead resistance levels at $14.46 to $18.

Inergy Midstream

Inergy Midstream (NRGM) owns, operates, develops and acquires midstream energy assets. Its current asset base consists of natural gas and NGL storage and transportation assets located in the Northeast region of the U.S. This stock closed up 3.1% at $25.06 on Friday.

Friday's Volume: 344,000

Average Volume: 208,135

Volume % Change: 115%

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From a technical perspective, NRGM jumped higher here right above some near-term support at $24 with above-average volume. This stock has been uptrending strong for the last few weeks, with shares soaring higher from its low of $21.03 to its intraday high on Friday of $25.06. During that uptrend shares of NRGM have been consistently making higher lows and higher highs, which is bullish technical price action. This stock has also seen extremely bullish upside volume flows during that move. Shares of NRGM are now quickly moving within range of triggering a major breakout trade. That trade will hit if NRGM manages to take out its all-time high at $26.01 with high volume.

Traders should now look for long-biased trades in NRGM as long as it's trending above $24 or above its 50-day at $23.02 and then once it sustains a move or close above its all-time high at $26.01 with volume that hits near or above 208,135 shares. If that breakout triggers soon, then NRGM will set up to enter new all-time high territory, which is bullish technical price action. Some possible upside targets off that breakout are $30 to $33.

DreamWorks Animation SKG

DreamWorks Animation SKG (DWA) is engaged in the development, production and exploitation of animated films and their associated characters. This stock closed up 6.5% to $25.87 on Friday.

Friday's Volume: 1.92 million

Average Volume: 852,200

Volume % Change: 127%

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From a technical perspective, DWA ripped higher here right above some near-term support at $24.04 and above its 50-day at $23.13 with heavy upside volume. This stock has been uptrending strong for the last four months and change, with shares soaring higher from its low of $15.90 to its recent high of $26.67. During that uptrend, shares of DWA have been consistently making higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of DWA within range of triggering a near-term breakout trade. That trade will hit if DWA manages to take out its 52-week high at $26.67 with high volume

Traders should now look for long-biased trades in DWA as long as it's trending above some near-term support levels at $24.04 or its 50-day at $23.13 and then once it sustains a move or close above its 52-week high at $26.67 with volume that hits near or above 852,200 shares. If that breakout triggers soon, then DWA will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $30 to $35.

Nationstar Mortgage

Nationstar Mortgage (NSM) services residential mortgage loans throughout the U.S. This stock closed up 2.8% at $42.16 on Friday.

Friday's Volume: 1.51 million

Average Volume: 1.17 million

Volume % Change: 50%

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From a technical perspective, NSM jumped higher here right off its 50-day moving average of $40.97 with above-average volume. This move is quickly pushing shares of NSM within range of triggering a near-term breakout trade. That trade will hit if NSM manages to take out some near-term overhead resistance at $44.35 with high volume.

Traders should now look for long-biased trades in NSM as long as it's trending above its 50-day at $40.97 or above more near-term support at $40, and then once it sustains a move or close above $44.35 with volume that's near or above 1.17 million shares. If that breakout triggers soon, then NSM set up to re-test or possibly take out its all-time high at $46.91. Any high-volume move above $46.91 will then give NSM a chance to hit or trend north of $50.

To see more stocks rising on unusual volume, check out the Stocks Rising on Unusual Volume portfolio on Stockpickr.

-- Written by Roberto Pedone in Delafield, Wis.

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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.