Stock Quotes in this Article: OREX, RNN, VSCI, NEO

DELAFIELD, Wis. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

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Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

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With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside.

Rexahn Pharmaceuticals

Rexahn Pharmaceuticals (RNN), a clinical stage biopharmaceutical company, engages in the discovery, development and commercialization of treatments for cancer, central nervous system disorders, sexual dysfunction and other medical needs. This stock closed up 18% to $1.18 a share in Thursday's trading session.

Thursday's Range: $1.01-$1.18

52-Week Range: $0.28-$1.85

Thursday's Volume: 18.77 million

Three-Month Average Volume: 6.83 million

From a technical perspective, RNN exploded higher here with heavy upside volume. This move sharp move to the upside is quickly pushing shares of RNN within range of triggering a near-term breakout trade. That trade will hit if RNN manages to take out some near-term overhead resistance at $1.18 to $1.20 with high volume.

Traders should now look for long-biased trades in RNN as long as it's trending above some key near-term support levels at $1 or above 97 cents per share and then once it sustain a move or close above those breakout levels with volume that hits near or above 6.83 million shares. If that breakout hits soon, then RNN will set up to re-test or possibly take out its next major overhead resistance levels at $1.60 to its 52-week high at $1.85.

Vision-Sciences

Vision-Sciences (VSCI), together with its subsidiaries, engages in the design, development, manufacture and marketing of endoscopy products. This stock closed up 9.3% to $1.40 a share in Thursday's trading session.

Thursday's Range: $1.33-$1.43

52-Week Range: $0.78-$1.50

Thursday's Volume: 158,000

Three-Month Average Volume: 136,134

From a technical perspective, VSCI gapped up sharply higher here with above-average volume. This spike higher on Thursday is quickly pushing shares of VSCI within range of triggering a big breakout trade. That trade will hit if VSCI manages to take out Thursday's high of $1.43 to $1.45 and then once it clears its 52-week high at $1.50 with high volume.

Traders should now look for long-biased trades in VSCI as long as it's trending above Thursday's low of $1.33 or above $1.20 and then once it sustains a move or close above those breakout levels with volume that hits near or above 136,134 shares. If that breakout triggers soon, then VSCI will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that breakout are its next major overhead resistance levels at $1.70 to $1.80, or even $2.

Neogenomics

Neogenomics (NEO) operates a network of cancer-focused testing laboratories providing genetic and molecular testing services to hospitals, pathologists, oncologists, urologists, other clinicians and researchers and other laboratories in the U.S. This stock closed up 7.2% to $4.30 a share in Thursday's trading session.

Thursday's Range: $4.11-$4.47

52-Week Range: $2.05-$4.69

Thursday's Volume: 615,000

Three-Month Average Volume: 270,866

From a technical perspective, NEO spiked sharply higher here right above its 50-day moving average of $3.82 with above-average volume. This move is quickly pushing shares of NEO within range of triggering a major breakout trade. That trade will hit if NEO manages to take out Thursday's high of $4.47 to its 52-week high at $4.69 with high volume.

Traders should now look for long-biased trades in NEO as long as it's trending its 50-day at $3.82 or above its 200-day at $3.40 and then once it sustains a move or close above those breakout levels with volume that hits near or above 270,866 shares. If that breakout triggers soon, then NEO will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $5.50 to $6.

Orexigen Therapeutics

Orexigen Therapeutics (OREX), a biopharmaceutical company, focuses on the development of pharmaceutical product candidates for the treatment of obesity. This stock closed up 2.2% to $6.89 in Thursday's trading session.

Thursday's Range: $6.73-$7.04

52-Week Range: $4.60-$7.84

Thursday's Volume: 2.46 million

Three-Month Average Volume: 2.62 million

From a technical perspective, OREX bounced notably higher here right above some near-term support at $6.50 with solid upside volume. This stock has been uptrending strong for the last month and change, with shares moving higher from its low of $5.28 to its intraday high of $7.04. During that move, shares of OREX have been consistently making higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of OREX within range of triggering a big breakout trade. That trade will hit if OREX manages to take out some key overhead resistance levels at $7.05 to $7.13 and then once it clears more resistance at $7.32 with high volume.

Traders should now look for long-biased trades in OREX as long as it's trending above $6.50 or above its 50-day at $6.05 and then once it sustains a move or close above those breakout levels with volume that hits near or above 2.62 million shares. If that breakout hits soon, then OREX will set up to re-test or possibly take out its 52-week high at $7.84. Any high-volume move above that level will then give OREX a chance to tag $9 to $10.

To see more stocks that are making notable moves higher, check out the Stocks Under $10 Moving Higher portfolio on Stockpickr.

-- Written by Roberto Pedone in Delafield, Wis.


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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including

CNBC.com and Forbes.com.

You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.