Stock Quotes in this Article: ENZ, ISR, RTIX, SPEX

DELAFIELD, Wis. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

>>5 Stocks Under $10 Set to Soar

Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

>>5 Stocks Insiders Love Right Now

With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside.

IsoRay

IsoRay (ISR) develops, manufactures, and sells isotope-based medical products and devices for the treatment of cancer and other malignant diseases primarily in the U.S. This stock closed up 6.2% to 85 cents per share a share in Thursday's trading session.

Thursday's Range: $0.78-$0.85

52-Week Range: $0.42-$1.19

Thursday's Volume: 1.50 million

Three-Month Average Volume: 833,827

From a technical perspective, ISR spiked sharply higher here right above some near-term support levels at 75 to 70 cents per share with strong upside volume. This stock recently pulled back from its 52-week high of $1.19 to just under 75 cents per share. Shares of ISR are now starting to bounce higher off its near-term support levels and the stock is starting to move within range of triggering a near-term breakout trade. That trade will hit if ISR manages to take out Thursday's high of 85 cents per share to some more key overhead resistance at 97 cents per share with high volume.

Traders should now look for long-biased trades in ISR as long as it's trending above support at 70 cents per share and then once it sustains a move or close above those breakout levels with volume that hits near or above 833,827 shares. If that breakout hits soon, then ISR will set up to re-test or possibly take out its 52-week high at $1.19.

Enzo Biochem

Enzo Biochem (ENZ), an integrated life sciences and biotechnology company, is engaged in the research, development, manufacture, and marketing of diagnostic and research products based on genetic engineering, biotechnology, and molecular biology. This stock closed up 2.1% to $2.88 a share in Thursday's trading session.

Thursday's Range: $2.78-$2.88

52-Week Range: $1.83-$3.63

Thursday's Volume: 873,000

Three-Month Average Volume: 174,956

From a technical perspective, ENZ jumped notably higher here right above its 50-day moving average of $2.60 with monster upside volume. This move is starting to push shares of ENZ within range of triggering a big breakout trade. That trade will hit if ENZ manages to take out some key near-term overhead resistance levels at $2.95 to $3.10 with high volume.

Traders should now look for long-biased trades in ENZ as long as it's trending above its 50-day at $2.60 or above its 200-day at $2.40 and then once it sustains a move or close above those breakout levels with volume that hits near or above 174,956 shares. If that breakout hits soon, then ENZ will set up to re-test or possibly take out its 52-week high at $3.63 to some past overhead resistance at $4.

RTI Surgical

RTI Surgical (RTIX), together with its subsidiaries, produces orthopedic and other surgical implants that repair and promote the natural healing of human bone and other human tissues. This stock closed up 3.3% to $3.42 a share in Thursday's trading session.

Thursday's Range: $3.25-$3.44

52-Week Range: $2.77-$5.11

Thursday's Volume: 135,000

Three-Month Average Volume: 285,963

From a technical perspective, RTIX spiked notably higher here right above its 50-day moving average of $3.16 with lighter-than-average volume. This move briefly pushed shares of RITX into breakout territory, after the stock flirted with some near-term overhead resistance at $3.43. Shares of RITX closed just below that level at $3.42. This move is starting to push shares of RTIX within range of triggering another breakout trade. That trade will hit if RTIX manages to take out Thursday's high of $3.44 to its 200-day moving average of $3.67 with high volume.

Traders should now look for long-biased trades in RTIX as long as it's trending above its 50-day at $3.16 or above $3 and then once it sustain a move or close above those breakout levels with volume that hits near or above 285,963 shares. If that breakout hits soon, then RTIX will set up to re-test or possibly take out its next major overhead resistance levels at $4 to $4.30, or even $4.50.

Spherix

Spherix (SPEX) operates as an intellectual property development company. The company provides a commercialization platform for protected technologies. This stock closed up 4.4% to $8.50 in Thursday's trading session.

Thursday's Range: $8.12-$9.00

52-Week Range: $4.07-$27.86

Thursday's Volume: 539,000

Three-Month Average Volume: 100,987

From a technical perspective, SPEX spiked sharply higher here back above both its 50-day moving average at $8.23 and its 200-day moving average at $8.35 with heavy upside volume. This move is quickly pushing shares of SPEX within range of triggering a near-term breakout trade. That trade will hit if SPEX manages to take out Thursday's high of $9 to some more near-term overhead resistance at $9.10 with high volume.

Traders should now look for long-biased trades in SPEX as long as it's trending above Thursday's low of $8.12 or above more near-term support just under $8 and then once it sustains a move or close above those breakout levels with volume that hits near or above 100,987 shares. If that breakout hits soon, then SPEX will set up to re-test or possibly take out its next major overhead resistance levels at $10.40 to $13.70.

To see more stocks that are making notable moves higher, check out the Stocks Under $10 Moving Higher portfolio on Stockpickr.

-- Written by Roberto Pedone in Delafield, Wis.


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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including

CNBC.com and Forbes.com.

You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.