Stock Quotes in this Article: SPPI, ZIOP, IBIO, CCXI

DELAFIELD, Wis. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

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Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

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With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside today.

Ziopharm Oncology

Ziopharm Oncology (ZIOP) is a biopharmaceutical company engaged in the development and commercialization of small molecule and synthetic biology approaches to new cancer therapies. This stock closed up 2.8% to $3.23 in Tuesday's trading session.

Tuesday's Range: $3.11-$3.26

52-Week Range: $1.49-$6.02

Thursday's Volume: 460,000

Three-Month Average Volume: 910,536

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From a technical perspective, ZIOP bounced notably higher here right off its 200-day moving average at $3.17 with lighter-than-average volume. This stock has been uptrending strong for the last six months, with shares moving higher from its low of $1.49 to its recent high of $3.50. During that move, shares of ZIOP have been making mostly higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of ZIOP within range of triggering a major breakout trade. That trade will hit if ZIOP manages to take out some near-term overhead resistance levels at $3.44 to $3.50 with high volume.

Traders should now look for long-biased trades in ZIOP as long as it's trending above its 50-day at $3.01 or above more near-term support at $2.75 and then once it sustains a move or close above those breakout levels with volume that hits near or above 910,536 shares. If that breakout triggers soon, then ZIOP will set up to re-fill some of its previous gap down zone from March that started at $5.

Spectrum Pharmaceuticals

Spectrum Pharmaceuticals (SPPI) is a commercial stage biotechnology company integrated in commercial and drug development operations and primarily in oncology and hematology. This stock closed up 4.7% to $8.42 in Tuesday's trading session.

Tuesday's Range: $8.04-$8.43

52-Week Range: $6.92-$13.52

Tuesday's Volume: 898,000

Three-Month Average Volume: 992,453

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From a technical perspective, SPPI spiked sharply higher here right off its 50-day moving average of $8.08 and into breakout territory above $8.32 with decent upside volume. This move is quickly pushing shares of SPPI within range of triggering another big breakout trade. That trade will hit if SPPI manages to take out Tuesday's high of $8.43 and then once it clears more resistance at $8.54 with high volume.

Traders should now look for long-biased trades in SPPI as long as it's trending above its 50-day at $8.08 or above more support at $7.83 and then once it sustains a move or close above those breakout levels with volume that hits near or above 992,453 shares. If that breakout hits soon, then SPPI will set up to re-test or possibly take out its next major overhead resistance level at $9.21. Any high-volume move above $9.21 will then give SPPI a chance to re-fill some of its previous gap down zone from March that started at $12.47.

ChemoCentryx

ChemoCentryx (CCXI) is a biopharmaceutical company engaged in discovering, developing and commercializing orally administered therapeutics to treat autoimmune diseases, inflammatory disorders and cancer. This stock closed up 7.1% to $6.42 in Tuesday's trading session.

Tuesday's Range: $5.85-$6.45

52-Week Range: $5.28-$14.96

Tuesday's Volume: 813,000

Three-Month Average Volume: 329,620

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From a technical perspective, CCXI spiked sharply higher here with above-average volume. This stock has been downtrending badly for the last month and change, with shares moving lower from its high of $14.75 to its recent low of $5.28. During that move, shares of CCXI have been making mostly lower highs and lower lows, which is bearish technical price action. That said, shares of CCXI are now starting to bounce off those recent lows and the stock is moving within range of triggering a near-term breakout trade. That trade will hit if CCXI manages to take out its recent gap down day high of $6.78 with high volume.

Traders should now look for long-biased trades in CCXI as long as it's trending above Tuesday's low of $5.85 or that recent low of $5.28 and then once it sustains a move or close above $6.78 with volume that hits near or above 329,620 shares. If that breakout triggers soon, then CCXI will set up to re-fill some of its previous gap down zone that started near $8.40. If that gap gets filled with volume, then CCXI could even tag $10 in the short-term.

iBio

iBio (IBIO) is a biotechnology company focused on developing vaccines and therapeutic proteins based upon its proprietary plant-based iBioLaunch Platform Technology. This stock closed up 6.5% to 48 cents per share in Tuesday's trading session.

Tuesday's Range: $0.46-$0.48

52-Week Range: $0.33-$1.24

Tuesday's Volume: 308,000

Three-Month Average Volume: 273,839

From a technical perspective, IBIO bounced sharply higher here right above some near-term support at 45 cents per share with above-average volume. This move is quickly pushing shares of IBIO within range of triggering a near-term breakout trade. That trade will hit if IBIO manages to take out some near-term overhead resistance levels at its 50-day moving average of 0.485 and then above more resistance at 50 cents per share with high volume.

Traders should now look for long-biased trades in IBIO as long as it's trending above some key near-term support at 44 cents per share and then once it sustains a move or close above those breakout levels with volume that hits near or above 273,839 shares. If that breakout triggers soon, then IBIO will set up to re-test or possibly take out its next major overhead resistance levels at its 200-day moving average of 55 cents per share to more resistance at 65 cents per share.

To see more stocks that are making notable moves higher today, check out the Stocks Under $10 Moving Higher portfolio on Stockpickr.

-- Written by Roberto Pedone in Delafield, Wis.


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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including

CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.