Stock Quotes in this Article: SKBI, HZNP, MEIP, RGLS

DELAFIELD, Wis. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

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Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

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With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside.

MEI Pharma

MEI Pharma (MEIP), a development-stage oncology company, focuses on the clinical development of therapeutics for the treatment of cancer. This stock closed up 3.4% to $8.41 in Tuesday's trading session.

Tuesday's Range: $8.07-$8.48

52-Week Range: $4.37-$12.45

Tuesday's Volume: 72,000

Three-Month Average Volume: 137,082

From a technical perspective, MEIP spiked notably higher here right above some near-term support at $8 with lighter-than-average volume. This stock has been consolidating and trending sideways for the last three months, with shares moving between $7.30 on the downside and $8.94 on the upside. This spike on Tuesday is starting to push shares of MEIP within range of triggering a big breakout trade above the upper-end its recent sideways trading chart pattern. That breakout will hit if MEIP manages to take out Tuesday's high of $8.48 to some more near-term overhead resistance at $8.94 with high volume.

Traders should now look for long-biased trades in MEIP as long as it's trending above $8 or above $7.50 and then once it sustains a move or close above those breakout levels with volume that hits near or above 137,082 shares. If that breakout triggers soon, then MEIP will set up to re-test or possibly take out its next major overhead resistance levels $10 to $10.95.

Skystar Bio Pharmaceutical

Skystar Bio Pharmaceutical (SKBI), through its subsidiaries, engages in the research, development, production, marketing and sale of veterinary health care and medical care products in the People's Republic of China. This stock closed up 8.2% to $4.08 in Tuesday's trading session.

Tuesday's Range: $3.63-$4.14

52-Week Range: $1.00-$6.50

Tuesday's Volume: 69,000

Three-Month Average Volume: 76,374

From a technical perspective, SKBI ripped sharply higher here back above its 50-day moving average of $3.87 with decent upside volume. This spike is starting to push shares of SKBI within range of triggering a major breakout trade. That trade will hit if SKBI manages to take out Tuesday's high of $4.14 to some more near-term overhead resistance at $4.67 with high volume.

Traders should now look for long-biased trades in SKBI as long as it's trending above Tuesday's low of $3.63 or above more support at $3.50 and then once it sustains a move or close above those breakout levels with volume that hits near or above 76,374 shares. If that breakout hits soon, then SKBI will set up to re-test or possibly take out its next major overhead resistance levels at $5 to $5.94.

Horizon Pharma

Horizon Pharma (HZNP), a specialty pharmaceutical company, through its subsidiaries, develops and commercializes medicines for the treatment of arthritis, pain and inflammatory diseases. This stock closed up 7.1% to $8.50 in Tuesday's trading session.

Tuesday's Range: $7.93-$8.52

52-Week Range: $1.97-$9.13

Tuesday's Volume: 1.19 million

Three-Month Average Volume: 1.63 million

From a technical perspective, HZNP spiked sharply higher here right above some near-term support at $7.63 and above its 50-day moving average of $7.32 with decent upside volume. This spike is quickly pushing shares of HZNP within range of triggering a major breakout trade. That trade will hit if HZNP manages to take out Tuesday's high of $8.52 to $8.85 and then once it clears its all-time high at $9.13 with high volume.

Traders should now look for long-biased trades in HZNP as long as it's trending above some near-term support at $7.63 or above its 50-day at $7.32 and then once it sustains a move or close above those breakout levels with volume that hits near or above 1.63 million shares. If that breakout hits soon, then HZNP will set up to enter new all-time-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $12 to $13.

Regulus Therapeutics

Regulus Therapeutics (RGLS), a biopharmaceutical company, focuses on the discovery and development of drugs that target microRNAs to treat various diseases in the U.S. This stock closed up 13.1% to $8.89 a share in Tuesday's trading session.

Tuesday's Range: $7.85-$8.95

52-Week Range: $4.70-$12.89

Tuesday's Volume: 293,000

Three-Month Average Volume: 193,260

From a technical perspective, RGLS skyrocketed higher here back above its 200-day moving average of $8.31 and into breakout territory above some near-term overhead resistance at $8.77 with strong upside volume. Market players should now look for a continuation move higher in the short-term if RGLS manages to take out Tuesday's high of $8.95 with strong volume.

Traders should now look for long-biased trades in RGLS as long as it's trending above Tuesday's low of $7.85 or above more support a $7.51 and then once it sustains a move or close above $8.95 with volume that hits near or above 193,260 shares. If we get that move soon, then RGLS will set up to re-test or possibly take out its next major overhead resistance levels $9.82 to $10.22.

To see more stocks that are making notable moves higher, check out the Stocks Under $10 Moving Higher portfolio on Stockpickr.

-- Written by Roberto Pedone in Delafield, Wis.


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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including

CNBC.com and Forbes.com.

You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.