Stock Quotes in this Article: CPRX, SIGA, SYN

WINDERMERE, Fla. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

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Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

With that in mind, let's take a closer look at a several stocks that are making large moves to the upside today.

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Siga Technologies

Siga Technologies (SIGA) is a biotechnology company engaged in the development and commercialization of pharmaceutical solutions for some of the most lethal disease-causing pathogens in the world, including smallpox, Ebola, dengue and Lassa fever. This stock is trading up 7.3% to $3.21 in recent trading.

Today’s Range: $3.00-$3.21

52-Week Range: $2.20-$3.89

Volume: 340,000

Three-Month Average Volume: 176,071

From a technical perspective, SIGA is ripping higher here right above it 200-day moving average of $2.88 with above-average volume. This move has started to push shares of SIGA into breakout territory, since the stock has cleared some near-term overhead resistance levels at $3.03 to $3.17.

Traders should now look for long-biased trades in SIGA as long as it’s trending above $3.03 or $3.17 with strong upside volume flows. I would consider any upside volume day that registers near or above its three-month average action of 17,071 shares. If SIGA can maintain that trend, then this stock will set up to re-test or possibly take out its next major overhead resistance levels at $3.38 to $3.57. Any high-volume move above $3.57 will then put $3.70 to $3.89 into focus for shares of SIGA.

Catalyst Pharmaceutical

Catalyst Pharmaceutical (CPRX) is a biopharmaceutical company engaged in the development and commercialization of prescription drugs targeting diseases of the central nervous system, with a focus on the treatment of drug addiction and epilepsy. This stock is trading up 6.1% to 54 cents per share in recent trading.

Today’s Range: $0.52-$0.55

52-Week Range: $0.37-$2.27

Volume: 219,000

Three-Month Average Volume: 884,200

From a technical perspective, CPRX is bouncing higher here right off its 50-day moving average of 50 cents per share. This move is quickly pushing shares of CPRX within range of triggering a near-term breakout trade. That trade will hit if CPRX manages to take out some near-term overhead resistance levels at 58 cents to 60 cents with high volume.

Traders should now look for long-biased trades in CPRX as long as it’s trending above its 50-day at 50 cents per share and then once it sustains a move or close above those breakout levels with volume that hits near or above 884,200 shares. If that breakout triggers soon, then CPRX will set up to re-test or possibly take out its next major overhead resistance levels which is the gap down day high from last November at 69 cents per share. Any high-volume move above 69 cents per share will then give CPRX a chance to re-fill some of that previous gap down zone that started at $1.50.

Synthetic Biologics

Synthetic Biologics (SYN) is a biotechnology company focused on the development of synthetic DNA-based therapeutics and innovative disease-modifying medicines for serious illnesses. This stock is trading up 2.1% to $1.90 in recent trading.

Today’s Range: $1.85-$2.00

52-Week Range: $1.46-$2.95

Volume: 212,000

Three-Month Average Volume: 57,716

From a technical perspective, SYN is bouncing modestly higher here right off its 50-day moving average of $1.80 with heavy upside volume. This stock has been uptrending strong for the last month and change, with shares moving higher from its low of $1.51 to its recent high of $2. During that move, shares of SYN have been mostly making higher lows and higher highs, which is bullish technical price action. That move is now quickly pushing shares of SYN within range of triggering a near-term breakout trade, which will hit if SYN manages to take out its 200-day at $1.96 and then once it clears more resistance levels at $1.99 to $2 and then $2.12 with high volume.

Traders should now look for long-biased trades in SYN as long as it’s trending above its 50-day at $1.80 and then once it sustains a move or close above those breakout levels with volume that hits near or above 57,716 shares. If that breakout triggers soon, then SYN will set up to re-test or possibly take out its next major overhead resistance levels at $2.40 to $2.55. Any high-volume move above $2.55 will then put its 52-week high at $2.95 into range for shares of SYN.

To see more stocks that are making notable moves higher today, check out the Stocks Under $10 Moving Higher portfolio on Stockpickr.

-- Written by Roberto Pedone in Winderemere, Fla.


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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Windermere, Fla., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including

CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.