Stock Quotes in this Article: ARIA, GNVC, RNA

DELAFIELD, Wis. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

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Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

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With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside.

Prosensa Holding

Prosensa Holding (RNA), a biotechnology company, is engaged in the discovery and development of RNA-modulating therapeutics for the treatment of rare genetic disorders. This stock closed up 8.3% to $5.06 in Thursday's trading session.

Thursday's Range: $4.66-$5.16

52-Week Range: $3.43-$34.55

Thursday's Volume: 247,000

Three-Month Average Volume: 287,900

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From a technical perspective, RNA spiked sharply higher here right above some near-term support at $4.55 with decent upside volume. This move is quickly pushing shares of RNA within range of triggering a major breakout trade. That trade will hit if RNA manages to take out Thursday's high of $5.16 to some more near-term overhead resistance levels at $5.37 to $5.44 with high volume.

Traders should now look for long-biased trades in RNA as long as it's trending above its 50-day at $4.33 or above more near-term support at $4.03 and then once it sustains a move or close above those breakout levels with volume that hits near or above 287,900 shares. If that breakout hits soon, then RNA will set up to re-test or possibly take out its next major overhead resistance levels at $6 to $7.30.

Ariad Pharmaceuticals

Ariad Pharmaceuticals (ARIA), an oncology company, focuses on the discovery, development, and commercialization of medicines for cancer patients. This stock closed up 6.4% to $7.26 in Thursday's trading session.

Thursday's Range: $7.00-$7.75

52-Week Range: $2.15-$23.00

Thursday's Volume: 53.58 million

Three-Month Average Volume: 26.46 million

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From a technical perspective, ARIA spiked sharply higher here with monster upside volume. This move is quickly pushing shares of ARIA within range of triggering a major breakout trade. That trade will hit if ARIA manages to take out Thursday's high and some key near-term overhead resistance at $7.75 with high volume.

Traders should now look for long-biased trades in ARIA as long as it's trending above Thursday's low of $7 or above more near-term support at $6.50 and then once it sustains a move or close above $7.75 with volume that hits near or above 26.46 million shares. If that breakout hits soon, then ARIA will set up to re-fill some of its previous gap-down zone from last October that started near $18. This massive gap sits just above $7.75, so ARIA could see a sizable move if the stock trades into that zone with volume.

GenVec

GenVec (GNVC) develops gene-based pharmaceuticals and therapies for the treatment of major medical needs. This stock closed up 7.3% to $2.49 in Thursday's trading session.

Thursday's Range: $2.30-$2.61

52-Week Range: $0.25-$2.89

Thursday's Volume: 553,000

Three-Month Average Volume: 401,528

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From a technical perspective, GNVC spiked sharply higher here right off some near-term support at $2.20 with above-average volume. This stock has been uptrending strong over the last four months, with shares soaring higher from its low of 25 cents to its recent high of $2.89. During that uptrend, shares of GNVC have been making mostly higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of GNVC within range of triggering a major breakout trade. That trade will hit if GNVC manages to take out Thursday's high of $2.61 to its 52-week high at $2.89 with high volume.

Traders should now look for long-biased trades in GNVC as long as it's trending above Thursday's low of $2.30 or above more near-term support at $2 and then once it sustains a move or close above those breakout levels with volume that hits near or above 401,528 shares. If that breakout triggers soon, then GNVC will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $3.50 to $4.

To see more stocks that are making notable moves higher, check out the Stocks Under $10 Moving Higher portfolio on Stockpickr.

-- Written by Roberto Pedone in Delafield, Wis.


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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including

CNBC.com and Forbes.com.

You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.