Stock Quotes in this Article: OSUR, PBTH, XNPT

DELAFIELD, Wis. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

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Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

>>5 Stocks Under $10 Set to Soar

With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside today.

Prolor Biotech

Prolor Biotech (PBTH) develops proprietary versions of already-approved therapeutic proteins. This stock closed up 0.9% to $6.55 on Friday.

Friday's Range: $6.44-$6.55

52-Week Range: $4.25-$6.56

Volume: 151,000

Three-Month Average Volume: 316,065

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From a technical perspective, PBTH trended higher here right above its 50-day moving average of $6.28 with lighter-than-average volume. This stock has been uptrending strong for the last three months, with shares marching higher from its low of $4.80 to its recent high of $6.56. During that uptrend, shares of PBTH have been making mostly higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of PBTH within range of triggering a major breakout trade. That trade will hit if PBTH manages to take out its 52-week high at $6.56 with high volume.

Traders should now look for long-biased trades in PBTH as long as it's trending above its 50-day at $6.28 or above some more key near-term support at $6.10 and then once it sustains a move or close above $6.56 with volume that hits near or above 316,065 shares. If that breakout triggers soon, then PBTH will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that breakout are 7.50 to $8.50.

OraSure Technologies

OraSure Technologies (OSUR) develops, manufactures, markets and sells oral fluid diagnostic products and specimen collection devices using its proprietary oral fluid technologies. This stock closed up 7.4% to $4.46 on Friday.

Friday's Range: $4.17-$4.47

52-Week Range: $3.75-$12.48

Volume: 866,000

Three-Month Average Volume: 453,058

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From a technical perspective, OSUR ripped higher here back above its 50-day moving average of $4.28 with above-average volume. This move is quickly pushing shares of OSUR within range of triggering a near-term breakout trade. That trade will hit if OSUR manages to clear some near-term overhead resistance levels at $4.60 to $4.62 and then once it takes out more resistance at $5.05 with high volume.

Traders should now look for long-biased trades in OSUR as long as it's trending above its 50-day at $4.28 or above Friday's low of $4.17 and then once it sustains a move or close above those breakout levels with volume that hits near or above 453,058 shares. If that breakout triggers soon, then OSUR will set up to re-test or possibly take out its next major overhead resistance levels at $5.50 to $6. Any high-volume move above $6 to $6.15 will then put $6.75 to $7 into range for shares of OSUR.

Xenoport

Xenoport (XNPT) is a biopharmaceutical company focused on developing and commercializing a portfolio of internally discovered product candidates with an initial focus on neurological disorders. This stock closed up 1.9% to $5.76 on Friday.

Friday's Range: $5.49-$5.78

52-Week Range: $4.61-$12.98

Volume: 382,000

Three-Month Average Volume: 538,267

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From a technical perspective, XNPT spiked modestly higher here right off its 50-day moving average of $5.49 with decent upside volume. This stock has been uptrending for the last few weeks, with shares moving higher from its low of $4.61 to its intraday high of $5.78. During that move, shares of XNPT have been consistently making higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of XNPT within range of triggering a major breakout trade. That trade will hit if XNPT manages to take out some near-term overhead resistance levels at $5.94 to its gap down day high at $6.10 with high volume.

Traders should now look for long-biased trades in XNPT as long as it's trending above its 50-day at $5.49 or above $5.20 and then once it sustains a move or close above those breakout levels with volume that hits near or above 538,267 shares. If that breakout triggers soon, then XNPT will set up to re-fill its previous gap down zone from May that started at $6.83. Any high-volume move above $6.83 would then put its next major overhead resistance level at $7.60 into range for shares of XNPT.

To see more stocks that are making notable moves higher today, check out the Stocks Under $10 Moving Higher portfolio on Stockpickr.

-- Written by Roberto Pedone in Delafield, Wis.

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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.