Stock Quotes in this Article: FOLD, KERX, THLD

WINDERMERE, Fla. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

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Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside today.

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Amicus Therapeutics

Amicus Therapeutics (FOLD) is a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of a new class of orally administered, small molecule drugs, for the treatment of a range of human genetic diseases. This stock is trading up 5.1% to $3.90 in recent trading.

Today’s Range: $3.65-$3.92

52-Week Range: $2.47-$7.18

Volume: 374,000

Three-Month Average Volume: 1.25 million

From a technical perspective, FOLD is ripping higher here right off some near-term support at $3.62 with lighter-than-average volume. This move is quickly pushing shares of FOLD within range of triggering a major breakout trade. That trade will hit if FOLD manages to clear some near-term overhead resistance levels at $3.92 to $4.27 with high volume.

Traders should now look for long-biased trades in FOLD as long as it’s trending above $3.62 to $3.47, and then once it sustains a move or close above those breakout levels with volume that hits near or above 1.25 million shares. If that breakout hits soon, then FOLD will set up to re-fill some of its previous gap down zone from December that started near $6. The first price target objective if FOLD gets into that gap is its 200-day moving average of $4.92.

Threshold Pharmaceuticals

Threshold Pharmaceuticals (THLD) is a biotechnology company focused on the discovery and development of drugs targeting the microenvironment of solid tumors as novel treatments for patients living with cancer. This stock is trading up 3.5% to $4.56 in recent trading.

Today’s Range: $4.40-$4.59

52-Week Range: $2.90-$9.28

Volume: 331,000

Three-Month Average Volume: 876,681

From a technical perspective, THLD is bouncing higher here right above some near-term support at $4.36 to $4.28 and back above its 50-day moving average of $4.46 with lighter-than-average volume. This move is quickly pushing shares of THLD within range of triggering a near-term breakout trade. That trade will hit if THLD manages to take out some near-term overhead resistance levels at $4.75 to $4.80 with high volume.

Traders should now look for long-biased trades in THLD as long as it’s trending above $4.36 to $4.28, and then once it sustains a move or close above those breakout levels with volume that hits near or above 876,681 shares. If that breakout triggers soon, then THLD will set up to re-test or possibly take out its next major overhead resistance levels at $5.54 to its 200-day moving average at $6.08.

Keryx Biopharmaceuticals

Keryx Biopharmaceuticals (KERX) is a biopharmaceutical company focused on the acquisition, development and commercialization of medically important pharmaceutical products for the treatment of cancer and renal disease. This stock is trading up 5.8% to $7.01 in recent trading.

Today’s Range: $6.56-$7.35

52-Week Range: $1.28-$9.98

Volume: 10.18 million

Three-Month Average Volume: 6.38 million

From a technical perspective, KERX is spiking higher here right off some near-term support at $6.55 to $6.50 with monster upside volume. This move is coming after shares of KERX recently sold off from its high of $9.98 to around $6.50 with heavy downside volume. Shares of KERX are now quickly moving within range of triggering a near-term breakout trade. That trade will hit if KERX manages to take out some near-term overhead resistance levels at $6.90 to $7.30 and then once it clears more resistance that sits just below $8. At last check, KERX has hit an intraday high of $7.35 and volume is well above its three-month average action of 6.48 million shares.

Traders should now look for long-biased trades in KERX as long as it’s trending above some key near-term support at $6.50, and then once it sustains a move or close above those breakout levels with volume that hits near or above 6.38 million shares. If that breakout hits soon, then KERX will set up to re-test or possibly take out its next major overhead resistance levels at $9 to $9.98. Any high-volume move above $9.98 will then push shares of KERX into new 52-week high territory, which is bullish technical price action. Some possible upside targets if KERX makes a new 52-week high soon are $11 to $12.

To see more stocks that are making notable moves higher today, check out the Stocks Under $10 Moving Higher portfolio on Stockpickr.

-- Written by Roberto Pedone in Winderemere, Fla.


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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Windermere, Fla., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including

CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.