Stock Quotes in this Article: ACHN, TTHI

DELAFIELD, Wis. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

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Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

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With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside today.

Transition Therapeutics

Transition Therapeutics (TTHI) is a product-focused biopharmaceutical company, developing therapeutics for disease indications with markets. This stock closed up 6% to $5.09 in Tuesday's trading session.

Tuesday's Range: $4.84-$5.09

52-Week Range: $1.90-$5.30

Thursday's Volume: 86,000

Three-Month Average Volume: 36,691

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From a technical perspective, TTHI ripped sharply higher here right off some near-term support at $4.80 with above-average volume. This move is quickly pushing shares of TTHI within range of triggering a major breakout trade. That trade will hit if TTHI manages t take out Tuesday's high of $5.10 and then once it takes out its 52-week high at $5.30 with high volume.

Traders should now look for long-biased trades in TTHI as long as it's trending above its 50-day at $4.46 or above more support at $4.20 and then once it sustains a move or close above those breakout levels with volume that hits near or above 36,691 shares. If that breakout hits soon, then TTHI will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $6 to $7, or even $8.

Achillion Pharmaceuticals

Achillion Pharmaceuticals (ACHN) is a biopharmaceutical company focused on the discovery, development and commercialization of innovative treatments for infectious diseases. This stock closed up 11.6% to $2.79 in Tuesday's trading session.

Tuesday's Range: $2.46-$2.79

52-Week Range: $2.26-$10.17

Tuesday's Volume: 4.40 million

Three-Month Average Volume: 2.66 million

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From a technical perspective, ACHN skyrocketed higher here right off some near-term support at $2.44 with heavy upside volume. This move is quickly pushing shares of ACHN within range of triggering a near-term breakout trade. That trade will hit if ACHN manages to take out some near-term overhead resistance levels at $2.81 to $2.98 with high volume.

Traders should now look for long-biased trades in ACHN as long as it's trending above some key near-term support levels at $2.44 or at $2.26 and then once it sustains a move or close above those breakout levels with volume that hits near or above 2.66 million shares. If that breakout hits soon, then ACHN will set up to re-test or possibly take out its gap down day high from September at $3.62. Any high-volume move above that level will then give ACHN a chance to re-fill some of its previous gap down zone that started near $7.50.

To see more stocks that are making notable moves higher today, check out the Stocks Under $10 Moving Higher portfolio on Stockpickr.

-- Written by Roberto Pedone in Delafield, Wis.


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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including

CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.